The Bioinformatics Services Division (BiSD) is located on the 350- acre North Carolina Research Campus (NCRC) In Kannapolis, North Carolina. The campus is a public-private venture that draws the world's leading researchers from both academia and industry. Our offices are located on the 3rd floor of the David H. Murdock Core Lab.
In an economic environment that forces many organizations to drastically reduce computational investments, BiSD provides a technological oasis.
High-Performance Computing Resources
At our site on the NCRC we maintain a 624-core Debian Linux cluster with Intel Xeon processors. Compared to most clusters, ours is designed with more memory per node making our cluster ideally suited to the high-memory demands of biological data. The general-purpose queue contains a mixture of 12- and 16-core nodes with eight gigabytes of memory per core (totaling 96 GB or 128 GB per node). The cluster also has a high-memory queue containing four servers that each contain either 24- or 32-cores and 512GB or 1TB of memory. For storage, the cluster has access to 750 TB via a shared file system. For connectivity, the cluster has both a gigabit Ethernet interconnect for communication as well as a 10Gb interconnect for storage. We also have access to three additional Red Hat Linux clusters that are located on our main University campus.
The Bioinformatics Services Division has purchased a number of commercial software licenses to aid in data analysis. Some of the commercial licenses included:
- GeneGo metacore, an integrated knowledge database and software suite for pathway analysis of experimental data and gene lists.
- Linguamatics i2e, text mining software that enables the extraction of relevant facts and relationships from Medline.
- CLC Bio, which provides some of the newest algorithms and analyses available for analyses of genomic, transcriptomic and epigenomic NGS data.
- Geneious Pro, a software platform that is able to search, organize and analyze genomic and protein information.
- Partek Genomics Suite, a single analysis solution for integrated genomics, which provides comprehensive support for microarrays and next generation sequencing.
- DNASTAR’s Lasergene Core Suite, a comprehensive DNA and protein sequence analysis software suite comprised of eight applications, which include functions ranging from sequence assembly and SNP detection.
- Umetrics SIMCA-P+, software is used for the process of designing experiments and also for multivariate data analysis.
- SAS program package for statistical analyses.
In addition to the commercial software services, we utilize many excellent open-source bioinformatics software tools which are installed in our Linux, MAC OS and Windows environments. Tools include a local instance of the Galaxy workflow system, numerous next generation DNA sequencing platforms, gene annotation software, transcriptome analysis tools and many more. If desired, the Bioinformatics Services Division is able to develop custom software scripts and programs where necessary.